The pair will go toe-to-toe on the undercard of the WBO super-middleweight title rematch between Arthur Abraham and Paul Smith.
Price, 31, will be returning to action following a six-month injury lay-off and is looking forward to the 10-round contest against the 34-year-old Brazilian.
???I can???t wait to get back in the ring and remind everybody what I???m all about,??? said the former British and Commonwealth champion, who has won 18 of his 20 fights.
???Costa Junior is exactly the type of opponent I wanted. He???s got a decent record, similar to my own, with 16 wins and only two defeats.
???Last year, he went 12 rounds with Christian Hammer, so we know he???s no mug. It will be another step up, but I think he will bring out the best in me. I???m confident I will get the win.
???The support from Liverpool will be fantastic. There will be loads of fans coming over to get behind Paul and myself. I’m looking forward to being a part of such a big card. It will set up me up nicely for a ???homecoming??? fight later this year.???
Promoter Kalle Sauerland said: ???2015 is going to be a huge year for Pricey. That starts in Berlin on February 21.
???Costa Junior is a serious opponent. With a convincing victory, we can send a message to all the heavyweights around the world ??? the big man is back and he means business!???