Djokovic tamed Raonic's formidable serve before humbling the Canadian 7-6 6-4 6-2 on Wednesday to set up a mouth-watering semi-final against defending champion Stan Wawrinka.
Eighth seed Raonic, who had a compeitive season at Grand Slam level in 2014, was supposed to offer the first real test for the top-seeded Serb but was completely outclassed under the lights at Rod Laver Arena.
After being edged in the tiebreak of the opening set, Djokovic broke Raonic early in the second set and twice in the third, without giving up a single break point on his own serve.
He closed out the match with a clinical volley and will play the man that ended his title defence at Melbourne Park in last year's quarter-finals.
Fans will hope for another brilliant match between Djokovic and Wawrinka, with memories of their five-hour epic encounter in this tournament back in 2013 one of the greatest seen on the Melbourne courts.