Pittsburgh are now a point behind Metropolitan Division leaders New York Islanders, and two points?? clear of third-placed Washington.
Comeau had missed two months through injury but quickly set up Patric Hornqvist’s score just 1:51 into the game before firing a one-timer past Petr Mrazek later in the first period.
David Perron and Nick Spaling also scored for Pittsburgh and Stephen Weiss scored for the Red Wings.
Daniel Sedin gave Vancouver Canucks an overtime victory over Chicago Blackhawks.
Set up by his brother Henrik, Sedin made it 5-4 with his second strike of the game.
Washington Capitals??? Joel Ward netted with 2:18 remaining on the clock to earn an overtime win over San Jose Sharks.