Midfielder Jordan Henderson was also left at home with an ankle problem and that will need to be assessed at the weekend.
Defender Mamadou Sakho has resumed training this week after a hip injury while full-back Glen Johnson could be back after illness meant he missed the trip to Istanbul.
Manchester City have a fully-fit squad.
Key midfielder Yaya Toure is poised to return after missing Tuesday’s Champions League loss to Barcelona through suspension.
Striker Wilfried Bony, who has made two substitute appearances in the past week, could make his first start since his ??25million move from Swansea.