The 26-year-old carded an opening round 66 to hold a share of the lead with Inbee Park following Thursday's running at the Sentosa Golf Course.
The Taiwanese golfer has endured a tough two years; at the start of 2013 she was the world number one, but finished the year a lowly 34th before plummeting to 83rd last year.
Having finished second at the LPGA Thailand last week, Tseng's position at the front of the field in Singapore was another welcome sign of a resurgence.
“Oh, it’s fun. It’s so much fun. Like I tell my friends, my parents on the website, they don’t have to scroll down to see my name. They can just see right on top the first page," Tseng joked about being atop the leaderboard.
Tseng revealed that she has adopted a new, positive attitude and that it is paying dividends.
“This year, I guess I change new trainer, new coach and I start working on mental more and more, and I feel like awareness myself, how I’m positioned right now, it actually helps me a lot, too,” she explained.
“And self talk is one of the biggest things out there, because like I say, I tried to be patient and if I don’t tell myself to be patient, it’s hard to be patient. I’m very, very happy. I’m happy that I’m playing the golf again. It’s not thinking or I’m working out there."