The Argentina international was sent off for a challenge on Aaron Lennon during Sunday’s 3-0 defeat at Everton and will be suspended for three games, joining striker Papiss Cisse on the sidelines as he serves the second stage of his seven-match ban.
In addition, head coach John Carver will have to contend with a crippling injury list which will deprive him of the services of defenders Steven Taylor (Achilles), Paul Dummett and Massadio Haidara (both knee), and midfielders Cheick Tiote (also knee), Mehdi Abeid (thigh), Siem de Jong (collapsed lung) and Rolando Aarons (thigh).
Midfielder Tomas Rosicky is expected to be back in the Arsenal squad for the trip after illness.
The Gunners have reported no fresh injury concerns following the midweek Champions League tie in Monaco, but manager Arsene Wenger will assess the fatigue levels of his players before deciding on any changes.
Club captain Mikel Arteta (ankle), Alex Oxlade-Chamberlain (hamstring), Jack Wilshere (ankle) and Mathieu Debuchy (ankle) all continue their rehabilitation.