Striker Nugent and winger Schlupp missed Saturday’s 1-0 win at Burnley with calf injuries and will be assessed.
Vardy scored the winner at Turf Moor but played following an injection in his foot and will be monitored, but Chris Wood is in the squad after being recalled from his loan at Ipswich.
Diego Costa could return from his four-match absence with a hamstring injury.
Chelsea boss Jose Mourinho was planning to make a late decision on whether to gamble by playing the striker, whose season has been punctuated by hamstring problems.
Oscar could be missing after suffering a blow during Sunday’s goalless draw at Arsenal which leaves the Blues needing six points to win the title, while striker Loic Remy (calf) is definitely out.