Elsewhere, various relegation candidates will be hoping for a positive result against their rivals for the drop.
Everton v Sunderland
The Toffees remain in contention for a top 10 finish after making a disastrous start to the season and will face a Sunderland side buoyed by last week’s victory over Southampton. The hosts were somewhat surprisingly defeated by Aston Villa last week and will be eager to atone for that result in their penultimate home match of the season. Still in 18th place, the Black Cats will be eager to gain some more points on Saturday, but may find it difficult to repeat their result from last week. Prediction: Everton 1-1 Sunderland.
Aston Villa v West Ham
Villa have put some light between themselves and the other relegation candidates in recent weeks but aren’t out of the proverbial woods yet. After securing their Premier League survival some weeks ago already, West Ham have pretty much given up on the season and are unlikely to trouble Tim Sherwood’s side this time around. Prediction: Aston Villa 3-1 West Ham
Hull v Burnley
Despite last week’s loss against Arsenal, Hull have picked up some valuable points in recent weeks even though they remain just one point above the relegation zone. Mathematically Burnley aren’t down yet, but anything other than three victories in the remainder of the season will be the end of them. Sadly, for Sean Dyche's side, their brief stay in the Premier League is likely to be confirmed at the Tigers this weekend, even though the hosts will be without Mohamed Diame. Prediction: Hull 1-0 Burnley
Leicester v Southampton
A run of five wins from six matches have resulted in Leicester scoot up the table after being rooted near its foot for the majority of the season. Southampton’s early season form is long-forgotten and while Ronald Koeman’s side continues to boast one of the meanest defences in the division, the goals have long since dried up. Prediction: Leicester 0-0 Southampton
Newcastle v West Brom
After losing their last eight matches in the league while looking largely disinterested, Newcastle all of a sudden find themselves in a real pickle. The Baggies have taken seven points from their last three matches but after last week’s victory at Old Trafford confirmed their Premier League participation for another season, chances are they will already have one eye on the upcoming off-season. If that is indeed the case, the Magpies may finally break their losing streak this week. Prediction: Newcastle 1-1 West Brom
Stoke v Tottenham
Stoke remain on target to breach the 50-point barrier for the first time in the club’s history in the Premier League and have an excellent chance to gain the three points required against Spurs on Saturday. A month ago Tottenham remained in contention for a Champions League spot, but after recording just two wins in their last seven matches, sixth seems to be the best Mauricio Pochettino’s side can attain this time around. Prediction: Stoke 2-1 Tottenham
Crystal Palace v Man Utd
Man United need four points to secure their fourth place and Champions League qualification and Louis van Gaal’s men are likely to pick up some of those points against Palace, who, like their opponents on Saturday, have lost their last three matches. If the hosts go ahead this might turn out to be an interesting encounter, but an early goal for the visitors will more than likely be enough. Prediction: Crystal Palace 0-2 Man United
Man City v QPR
Neither side are playing particularly well at the moment, but a misfiring Man City should still be far too strong for a Rangers team that will be confirmed as relegated with a loss. Anything other than a comfortable win for last season’s winners will be something of an upset. Prediction: Man City 3-0 QPR
Chelsea v Liverpool
Having wrapped up the Premier League title last week, Chelsea may be slightly less motivated for Liverpool’s trip to Stamford Bridge on Sunday than they would have been otherwise. Nevertheless, Jose Mourinho’s sides can seldom be accused of being disinterested and Liverpool’s visit to London should be no different. The Reds remain in with a slight chance of pipping Man United for fourth spot and the Red Devils’ result the day before may well have a significant bearing on how driven Brendan Rodgers’ side is for this match. Prediction: Chelsea 1-1 Liverpool
Arsenal v Swansea
With nine wins and a draw from their last 10 matches, the Gunners are the form team in the league and had their resurgence taken place a few weeks earlier, they may have been genuine challengers for the title. Swansea continue to impress and have eighth place already sewn up. Should Spurs or Saints lose on Saturday, Garry Monk’s side may have an outside chance of finishing seventh, although a defeat themselves on Monday night would bring an end to their hopes of European qualification. Prediction: Arsenal 2-1 Swansea.