Semesa Rokoduguni will win his second England cap in two years when they face Fiji at Twickenham on Saturday.
The Bath wing earned his first cap against New Zealand in 2014. Teimana Harrison starts at flanker and is the only change to the England pack that helped seal a first victory over South Africa in 10 years with uncapped lock Charlie Ewels named among the replacements.
"We’ve picked a side we believe can beat Fiji," England coach Eddie Jones said.
Jonathan Joseph returns to the team at outside-centre with Elliot Daly switching to the wing, while Alex Goode starts at full-back for England.
Back row Nathan Hughes is named among the replacements along with Exeter Chiefs back Henry Slade and Worcester Warriors centre Ben Te’o.
"England at Twickenham is the game Fiji will have targeted on their tour. They are one of the iconic rugby nations of the world and we respect them enormously," Jones edded.
"They bring flair and an unbridled enthusiasm to move the ball at pace with running skills – if the game becomes unstructured they can be very a dangerous team. They’ll come to Twickenham with no fear and hungry to cause an upset.
"While we were satisfied with last week’s result against South Africa, there was plenty to improve on. We want a much more complete performance on Saturday – we want to be in total control of the game and tidy-up the things we didn’t do well enough last weekend. We’re looking forward to it."
England: 15 Alex Goode, 14 Semesa Rokoduguni, 13 Jonathan Joseph, 12 Owen Farrell, 11 Elliot Daly, 10 George Ford, 9 Ben Youngs, 8 Billy Vunipola, 7 Teimana Harrison, 6 Chris Robshaw, 5 Courtney Lawes, 4 Joe Launchbury, 3 Dan Cole, 2 Dylan Hartley, 1 Mako Vunipola
Replacements: 16 Jamie George, 17 Joe Marler, 18 Kyle Sinckler, 19 Charlie Ewels, 20 Nathan Hughes, 21 Danny Care, 22 Ben Te’o, 23 Henry Slade