Wie has had a torrid time since winning her first major title at Pinehurst last year: struggling with illness and injury, the 25-year-old is still waiting for her first top 10 finish in that time.
"It's definitely been a tough year with my game," Wie said.
"It's definitely not been as good as I want to be. I've been struggling with a couple of injuries and illnesses.
"But at the same time, I'm taking it day-by-day. Every day feels better than the day before. I'm definitely feeling better than I have been before.
"It feels good. I'm staying positive and just trying to improve a little bit here and there every day."
While the lay-out of the 6,400-yard Lancaster Country Club layout in Pennsylvania is a demanding one, it may well play into the hands of Wie, who is known for her long drives and putting prowess.
"I think it's a great golf course. It's a great layout. You definitely have a good mix of holes where you have long irons into some holes, you have very long par-threes," she added.
Wie added that she feels inspired by the American team who won the Women’s World Cup at the weekend when the US beat Japan 5-2.
"It was pretty amazing. I was pretty stoked on that, especially how the game went," Wie continued.
"Really great motivation, especially this year being the Solheim year. We definitely looked to them for inspiration and motivation … It definitely gave me goose bumps."
Wie may be one of the tournament favourites but two-time champion Park is definitely the strong favourite to lift the title, having returned to the top spot on the LPGA rankings following her victory at the Women's PGA Championship last month.
Park, who has six major victories to her name, reached the rankings summit for the third time in her career.
"It's my third time being here, I don't feel that much pressure anymore," said Park.
"I feel like number one or two, what's the difference?
"I'm just playing good golf and I don't need to show anybody anything. I just try to play my own golf and just not try to do something for other people.
"I definitely really do care about the major championships. When I come to major championships, I work extra hard and I try to look at the course a little bit better," she said.
Park’s predecessor, New Zealand teenager Lydia Ko, hopes to bounce back from her disappointment at the PGA Championship, where she missed the cut on the LPGA Tour for the first time after qualifying for the weekend in 53 consecutive events.
"Obviously I was really excited for that week, disappointed with the way it ended on a Friday," Ko admitted.
"I just kind of have to forget about it, just be excited again."