The Lions have included number eight and captain Warren Whiteley in their enlarged squad for this weekend's fixture against the Crusaders.
Whiteley, who has been sidelined over recent weeks with a shoulder injury, has progressed ahead of schedule since sustaining the problem.
It would be a significant boost for the Lions if he was to return, with head coach Johan Ackermann set to recall his first-choice team for Saturday's game. He rested the entire side last week against the Jaguares in order to keep them fresh for their Super Rugby quarter-final.
The Lions landed back in Johannesburg on Monday and will now prepare to face the Crusaders, with the team being named on Thursday.
Lions squad: Dylan Smith, Corné Fourie, Julian Redelinghuys, Jacques van Rooyen, Armand van der Merwe, Malcolm Marx, Franco Mostert, Andries Ferreira, Lourens Erasmus, Warren Whiteley, Ruan Ackermann, Warwick Tecklenburg, Jaco Kriel, Cyle Brink, Francois de Klerk, Ross Cronjé, Elton Jantjies, Jaco van der Walt, Rohan Janse van Rensburg, Courtnall Skosan, Ruan Combrinck, Andries Coetzee, Sylvian Mahuza, Howard Mnisi, Lionel Mapoe.