The on-loan England full-back missed Saints’ 1-1 draw with parent club Chelsea on December 28 but will slot straight back in with teenager Matt Targett dropping to the bench.
Saints have no new injury concerns but will miss influential France midfielder Morgan Schneiderlin, who is suspended after picking up a red card against Chelsea.
Danny Welbeck (thigh) is a doubt for Arsenal, while fellow forward??Olivier Giroud continues to serve a three-match suspension, so Theo??Walcott or Lukas Podolski could come into the attack.
Czech midfielder Tomas Rosicky is expected back in the squad having been rested??for the midweek win at West Ham, but Aaron Ramsey (hamstring), Mikel Arteta??(calf), Mesut Ozil (knee), Abou Diaby (calf), Jack Wilshere (ankle) and Serge??Gnabry (knee) all remain sidelined.