Main draw action got under way at the Aegon International on Monday, with American Donald Young and South African Kevin Anderson among those to advance.
Young secured his place in the second round with a 6-4, 3-6, 6-3 victory over local hope Kyle Edmund. The World No 47 was able to battle back from a break down in the decider, turning the tables with two breaks of his own to consign Edmund to defeat.
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Young moves on to face compatriot Jared Donaldson, who saved match point before upsetting eighth seed Diego Schwartzman 7-6 (7-5), 3-6, 7-5 in two hours and 47 minutes.
Anderson, meanwhile, continued his comeback from a series of injury troubles with a solid 6-3, 6-1 victory over Thomaz Bellucci.
The lanky former World No 10 struck 11 aces and won 24 of his 26 first-service points to set up a second-round clash with the winner of the match between Richard Gasquet and Frances Tiafoe.
Top seed Novak Djokovic will begin his campaign on Wednesday when he takes on qualifier Vasek Pospisil, who reached the second round by beating Jiri Vesely 6-3, 6-4.
Other winners on Monday included Robin Haase, Bernard Tomic and Cameron Norrie.