World No 106 Ward reached the semi-finals of the Wimbledon warm-up tournament in 2011 while Edmund, 20, has recently climbed to 121st in the rankings after qualifying for the main draw of the Australian Open.
The 28-year-old Ward and Edmund will join the likes of British Number 1 Andy Murray, Rafael Nadal, Stan Wawrinka and Marin Cilic at the tournament, which takes place from June 15-21.
The third wild card went to Australia’s four-time winner Lleyton Hewitt, this year making his 16th and last appearance at Queen’s ahead of his retirement from tennis.
Tournament director Stephen Farrow said: “James made a huge impression on the crowds at the Aegon Championships with his run to the semi-finals in 2011, and Kyle is an exciting young British talent.
“The field of players this year is one of the strongest we have ever assembled.
“With so many highly-ranked players, one of our greatest champions in Lleyton Hewitt, young stars like Nick Kyrgios, and now two British wild cards, we can’t wait for the tournament to begin.”