Richard Gasquet has been forced to withdraw from next week's Malaysia Open, while Ivo Karlovic and Nicolas Almagro have been handed wild cards.
The exact nature of the world number 11's injury is not known, but tournament director Nick Freyer has confirmed that he will not take his place in the draw.
“The tournament respects Richard’s decision to not compete when his body and mind is not up to the task,” said Fryer.
The big-serving Karlovic replaces Gasquet, while Almagro and 20-year-old Ramkumar Ramanathan of India have also been added to the line-up.
"We warmly welcome [Gasquet's] replacement, the "King of Serves", Ivo Karlovic on his inaugural visit to Malaysia,” added Fryer.
“Ivo is a player no other player wants to be drawn against, especially as he celebrates arguably his best year on Tour. My advice to fans watching any of his matches live is not to blink when Ivo serves… because they will miss it.
“At the same time, we welcome back our second wild card recipient and former top-ten player, Nicolas Almagro, who is playing his way into form after injury and also extend a welcome and opportunity to Ramkumar Ramanathan as he develops his young career.”
Karlovic has been named as the second seed at the event, which takes place at the Putra Stadium in Bukit Jalil, with Spaniard David Ferrer the top seed.