The Aprilia team will feature a special livery in support of charity at the MotoGP finale this weekend.
The RED charity was founded by U2 frontman Bono and activist Bobby Shiver in 2006 and raises funds for the Global fund, who fights AIDS tuberculosis and malaria.
Those three diseases are the three biggest killers in Africa and over 70 million people have been impacted on by the prevention and treatment by the Global Fund.
Not only will the machines of Alvaro Bautista and Stefan Bradl be red, but the entire Aprilia team will be donned in red racing suites.
The hashtag #RideRED will also be created for the Valencia race.