The 33-year-old Cameroonian is poised to officially swap Everton for Genoa as Samp bid to harness his firepower and qualify for the Champions League, and he was in the Marassi stands on Sunday.
Eder’s early opener temporarily boosted them into third place but Franco Vazquez hit back after the break and eighth-placed Palermo were unlucky not to turn their second-half dominance into a victory.
But with 34 points from 20 games, Sinisa Mihaljovic’s Samp climb above Napoli and into fourth place.
Paul Pogba scored one goal and created another as leaders Juventus beat Chievo 2-0.
The former Manchester United midfielder unlocked a tense battle in Turin with a well-struck opener on the hour mark before helping Stephan Lichtsteiner tuck away a second in the 74th minute.
The victory boosts Massimiliano Allegri’s men eight points clear of second-placed Roma ahead of the capital club’s Sunday night meeting with Fiorentina.
Emiliano Moretti’s last-gasp winner earned Torino a surprise 1-0 victory at Inter Milan.
Moretti headed home his first goal of the season deep into stoppage time at San Siro to push Inter further away from the hunt for a third-placed finish.
Inter, who have won just one of their last five league games, have subsequently dropped to ninth.
A late goal from substitute Alejandro Rodriguez allowed Cesena to halt an 18-match winless run with a 2-1 triumph over fellow strugglers Parma.
The game at Stadio Ennio Tardini looked to be heading for a draw after Emmanuel Cascione’s own goal with 14 minutes remaining cancelled out Nico Pulzetti’s opener.
However, Rodriguez came to the rescue for the visitors, scoring the winner one minute from time to hand Cesena their first win since the opening day.
Elsewhere on Sunday afternoon, the well-travelled Javier Saviola opened his goalscoring account for Hellas Verona, his 53rd-minute goal proving enough to secure a 1-0 home victory over Atalanta.