Barca, who are two points clear of Real Madrid at the top of the standings, have five games remaining ahead of Tuesday night’s clash with 13th-placed Getafe.
“Our calendar looks good from afar, but then you have to go out and play the game,” Luis Enrique told his club’s official website. “The five games left have their own challenges.
“The most important stretch is coming up.”
Barcelona, 2-0 winners over city rivals Espanyol at the weekend, have lost just two of their 16 league games at the Nou Camp this season, while Getafe have lost their last two league games.
“The most important thing is that we have survived another week and we still depend on ourselves,” Luis Enrique said. “At this stage of the campaign, it’s all about the wins and points.”
Real Madrid will go after a sixth consecutive win in La Liga when they host 16th-placed Almeria on Wednesday.
Carlo Ancelotti’s Real won 4-2 at Celta Vigo last time out, with in-form Javier Hernandez scoring twice in that game.
The Mexican forward, on loan from Manchester United, has scored four goals in the last four games, including the winner against Atletico that saw his side progress 1-0 on aggregate to the last four of the Champions League.
Atletico Madrid bounced back from that quarter-final elimination in Europe with a 3-0 triumph over Elche on Sunday.
The defending Spanish champions are third and travel to the El Madrigal stadium to face Villarreal, who sit sixth in the standings and are in the midst of a seven-match winless run.
Fourth-place Sevilla travel north to face strugglers Eibar on Wednesday.
Eibar have lost four of their last five league games to fall to 16th place.
Sevilla hold the last Champions League qualifying spot and are one point clear of Valencia, who have a game in hand.
Valencia host Granada on Monday before heading to Madrid to face Rayo Vallecano on Thursday.
Malaga and Athletic Bilbao are seventh and eighth, respectively, and looking to maintain their push for European football.
Athletic host Real Sociedad on Tuesday in a Basque duel. David Moyes’ La Real are without a win since March 22 and have collected three points since to fall to 12th position.
Malaga take to the road and face Celta Vigo in Galicia on Wednesday looking to reduce their six-point gap with Villarreal.
Cordoba must win at Levante on Tuesday in order to keep their faint hopes of staying in the Primera Division next season alive.
The Andalusian outfit are bottom of the standings, 11 points adrift of safety with 15 points still up for grabs.
A win at home to Deportivo on Wednesday would see Elche increase their gap over the drop zone to eight points.
Elche have won two of their last three league games to climb to 14th place while Depor are 18th, two points adrift of safety.
Granada, who are winless since March 7, host Espanyol on Thursday hoping for a result as they currently sit 19th and six points from safety.