The Trotters managed to hold the Reds to a goalless draw at Anfield to force the replay, and Crystal Palace lie in wait for the victor.
Brendan Rodgers has managed to oversee a change in fortunes for the Reds after a disappointing start to the season.
Two defeats in 17 in all competitions has revitalised the Anfield faithful, but Bolton will be no pushovers on their own turf.
Neil Lennon has himself improved his new side???s form, giving the Lancashire outfit a chance of a play-off push.
Bolton’s squad is depleted by injuries, with a hamstring tear seeing Darren Pratley join the likes of??Adam Bogdan, Emile Heskey, Marc Tierney, Mark Davies and Max Clayton on the??sidelines.
Striker Craig Davies could return from an injury of his own but former Red Emile Heskey is still struggling with a hamstring injury.
Only players registered prior to the original tie are eligible so Trotters boss??Neil Lennon is unable to call on new signings Ben Amos, Adam Le Fondre,??Rochinha, Barry Bannan, Simeon Slavchev, Filip Twardzik or Saidy Janko.
Liverpool captain Steven Gerrard is fully fit after sitting out the weekend with a tight hamstring.
Striker Daniel Sturridge, who scored in a 22-minute substitute appearance against West Ham on Saturday after a five-month lay-off, is likely to be on the bench again.
Some fringe players could get a rare start as manager Brendan Rodgers, with a Merseyside derby to come, looks to give some of his first-choice stars a much-needed rest as he did in the original meeting.