China gave Uzbekistan plenty of space in their opening salvos, appearing to look for their chances on the counter attack.
Uzbekistan had the first real chance of the match just before the 20 minute mark when a cross was almost knocked in thanks to a deflection, but the unflappable Wang cleared to keep the scoreline at 0-0.
Uzbekistan opened the scoring in the 22nd minute when Odil Ahmedov went on a run into the box, faked to the left and shot in on the right to hit Wang inside the China goal.
China immediately changed their strategy after the goal, pushing their men forward to look for the equaliser.
Despite dominating after the Ahmedov's strike, China struggled to find enough space. Their best chance came on the stroke of half time, as a Yu Hai headed an excellent cross in, only to be denied by good keeping from Nesterov.
China were clearly looking for the equaliser in the second half, and after pushing for almost 10 minutes found the equaliser in the 54th minute. Gao Lin sent an unusual cross in for Wu Xi, who made no mistake as he slammed the ball into the back of the net.
In the 66th minute, not even two minutes after coming on as a substitute for Gao Lin, Sun Ke scored to give China the lead. Ke took a run to the box, shooting from outside he slipped the ball into the back of the net.
China didn't take their foot off, coming close to a third goal in the 75th minute as a sailing cross into the box dropped just in time, but the resulting shot just went over.
In the final minutes China's defence parked the bus, and several desperate attempts from Uzbekistan to find an equaliser came to nothing.
The result saw China top Group B and secure their place in the Asian Cup quarter-finals where they will face either Australia or South Korea.