A first half penalty by Persepolis captain Mohammad Noori handed the Iranian side a 1-0 victory in their Group A encounter in the AFC Champions League against Bunyodor on Tuesday.
The spot kick was awarded after striker Mehdi Taremi was fouled inside the box and the midfielder stepped up to convert his second penalty in as many matches.
The Uzbek side largely dominated the rest of the match, possession-wise at least, but couldn't find a way back in the match.
In the early phase of the match, the hosts had the better of it too but struggled to create any clear-cut chances – a hopeful punt from range by midfielder Samir Bekric was the closest they came before Noori broke the deadlock on 20 minutes.
The hosts started the second half much brighter and almost equalised eight minutes after the break when Vokhid Shodiev's header from close range rebounded from the head of goalkeeper Sousha Makani before the Persepolis defense cleared.
The rest of the match was played almost exclusively in the visitors half and while Bekric and Artyom Filiposyan went close in the final quarter of the match, they were unable to find the back of Makani's net.
Persepolis are top of Group A with two wins from two.