However, even though Vahid Halilhodzic's first game as Japan coach was a success, he looked less than impressed with the Samurai Blue's performance in the first half as they wasted numerous opportunities to take the lead.
Debutant Kengo Kawamata came the closest to giving Japan the lead in the first half as his header hit the crossbar in the 20th minute.
With Tunisia managing to survive a barrage of shots from Japan in the first half, they looked a lot more confident in the second.
But, their confidence began to wane when Honda and Shinji Kagawa were introduced in the 60th minute, along with Okazaki a little while later.
The trio immediately had an impact as they sliced their way through Tunisia's defence time and time again.
Their aggression and attacking mentality paid off in the 78th minute when Okazaki spotted Honda's deep cross and headed the ball into the goal at the far post.
After having set up Japan's first goal, Honda decided to reward himself with a goal of his own just four minutes later when Tunisia keeper Moez Ben Cherifia pushed the ball right into his path following a cross by Kagawa.
Japan almost scored a third before the final whistle was blown, but debutant Takashi Usami's curling shot hit the post.
Japan's next international friendly will be against Uzbekistan on March 31, while Tunisia will take on China the very same day.