Hong Kong outfit Kitchee are two points behind Gomez's team and Johor need only to match or better Kitchee's result against Kingfisher East Bengal in Tuesday's other tie to ensure they clinch the group and a home draw in the one-off Round of 16 tie.
Newly-appointed Gomez plans on making a statement in his first continental outing with his new club.
"It is a very important game, and we need to win it. To secure first position in the group is very important for us," said the Argentine, who last month led South China to their own first place finish in Group G.
"From what I have seen, Johor have a group of very good players, but it is my job to make them improve further.
"To achieve the objective of finishing first, I am prepared to field my strongest players."
Balestier coach Marko Kraljevic is still keen to see his players sign off in style despite having no chance of qualifying for the last 16.
"Every game of the tournament I put out my best eleven and this match will be no different because we want to fight to finish third in the group," said Kraljevic.
"Johor are a good team and everyone in this club wants to pit himself against such quality sides."
Kitchee coach Jose Molina is expecting his side to go all out for the win on Tuesday.
"We are very close to the end of our domestic season now and the team is in very good condition," he said.
"The team is ready for another final this weekend and all I went now is for this team to show some good performances in these remaining few matches.
"The weather condition in Hong Kong now is really difficult but hopefully we will be lucky have a sunnier day on Wednesday," he added.