The Italian striker hit a sensational strike on four minutes to give Valencia an early lead against Zinedine Zidane’s side.
Collecting a cross with his back to goal near the penalty spot, the 25-year old spun and connected with a curling effort that flew into the net giving Madrid keeper Keylor Navas no chance.
He now has two goals in his last two games for Valencia after scoring against Athletic Bilbao at the weekend.
It’s a far cry from the goal-shy striker who started the season at West Ham and failed to score in 11 appearances, or 572 minutes, for the Hammers before he was moved onto Spain in the January transfer window.
Unsurprisingly, Zaza’s goal was quick to garner the attention of West Ham fans on social media.
Why has Zaza turned into Aguero
— West Ham Transfers (@westhamtransfer) February 22, 2017
— Matthew Galea (@mg91) February 22, 2017
Simone Zaza has now scored with both of his last two shots on target for Valencia.
No stopping this one. ? pic.twitter.com/9DoPDAqts8
— Squawka Football (@Squawka) February 22, 2017
Oh so this is what Simone Zaza does
— Ryan Catanese (@rcatanese) February 22, 2017
So that's proper Simone Zaza, putting Valencia in front with a belter v Real Madrid, rather than the lookalike who turned up at West Ham
— Andy Brassell (@andybrassell) February 22, 2017
All 572 minutes for West Ham – 0 goals.
His last 49 minutes for Valencia – 2 goals.
— bet365 (@bet365) February 22, 2017
Slaven Bilic must be watching and wondering what could have been.