The pair came face to face in the 'City of Angels' ahead of the their highly-anticipated $300 million blockbuster fight on May 2 at the MGM Grand in Las Vegas.
Mayweather was so pumped up about the fight that he even went on to say the world will stop to witness the "biggest fight in boxing history".
"Pacquiao is one of the best fighters of the era," Mayweather said at the press conference on Wednesday night. "I think we couldn't shoot at a better time.
"I'm in the gym right now working, dedicating myself to my sport and pushing myself to the limit because I have never wanted to win a fight more in my life.
"He wants to win just as the same as I do. One thing I do know about any sport is when you lose once it's in your mind. When you lose twice, it's in your mind.
"From day one I was told to push myself to the limit, to be a winner. We tried to make this fight happen in the past but we kept bumping heads about random blood testing. We finally resolved everything.
"May 2, that's when the world stops. Mayweather-Pacquiao, the biggest fight in boxing history."
Mayweather, who is currently a five-division world champion, will be heading into the fight with a 47-0 record, which includes 26 knockouts.
Pacquiao has won titles in eight divisions and will be looking to snap Mayweather's unbeaten streak while holding a 57-5 record, which includes 38 knockouts.