Ortiz smashed up a couple of dug-out telephones with his bat after taking issue with a strike called against him by umpire Tim Timmons in the seventh innings. It caused him to be ejected from the game that Boston won well, largely thanks to the efforts of Drew who went deep in the fourth and sixth innings.
They remain behind the Tampa Bay Rays in the American League West though, having ceded first place on Friday. Tampa Bay preserved their leading status thanks to a 1-0 win against the Yankees in New York.
Chris Carter's three-run homer helped the Houston Astros to knock over the Toronto Blue Jays 8-6, while the Minnesota Twins beat the Seattle Mariners 4-0 and a first-inning home run from Michael Bourn sufficed as the Cleveland Indians edged the Texas Rangers 1-0.
AL West leaders the Oakland Athletics had a two-run homer from Derek Norris to thank for their 3-1 win over the Los Angeles Angels while the Kansas City Royals pipped the Chicago White Sox 1-0.
In inter-league duelling, the AL Central front-running Detroit Tigers imposed themselves on the Philadelphia Phillies, winning 10-0 with homers from Matt Tuiasosopo and Miguel Cabrera.
The Atlanta Braves saw off the St Louis Cardinals in a tightly fought battle between two teams heading their respective divisions in the National League. The 2-0 win was earned by Andrelton Simmons' two-run double in the eighth inning.
NL West leaders the Los Angeles Dodgers overcame the Cincinnati Reds 4-1, steered to their win by Skip Schumaker's two-run homer.
Nate Schierholtz's home run gave the Chicago Cubs a 1-0 win against the San Francisco Giants, while home runs from Bryce Harper, Ian Desmond and Denard Span were lapped up by a home crowd as the Washington Nationals beat the New York Mets 4-1.
The Pittsburgh Pirates beat the Miami Marlins, while Chris Denorfia, Andrew Cashner and Chase Headley all went over the wall as the San Diego Padres pummelled the Arizona Diamondbacks 12-3 and the Milwaukee Brewers came out on top by a 7-5 margin in a rain-interrupted game against the Colorado Rockies in Denver.