Home runs from Mark Ellis and Yasiel Puig in the extra inning put paid to Toronto's hopes of toppling a team who have now won 23 of their last 28 games.
Behind them in the NL West, second-placed Arizona Diamondbacks suffered a 7-6 defeat at the hands of the Chicago Cubs, for whom Nate Schierholtz was outstanding with a career-high five runs. Arizona had fought back from 6-0 down but still ended up empty-handed.
Elsewhere in the National League, the St Louis Cardinals beat the Philadelphia Phillies 11-3, while Tim Hudson suffered a broken ankle in a collision with Eric Young Jr in the eighth inning of the Atlanta Braves' 8-2 win over the New York Mets.
Braves pitcher Hudson was covering first base and beat Young to the mark but received a sorry punishment for his troubles, with reports indicating he will miss the rest of the season.
Home runs from Evan Gattis, Dan Uggla and Andrelton Simmons guided Atlanta to their emphatic win.
The Philadelphia Phillies were 4-2 winners against the Washington Nationals, while the Milwaukee Brewers won for the first time since Ryan Braun received a 65-game on Monday, beating the San Diego Padres 3-1, and the Colorado Rockies edged the Miami Marlins 2-1.
The Cincinnati Reds inflicted an 8-3 defeat on the San Francisco Giants.
In the American League, the Seattle Mariners saw their eight-game winning streak ended in resounding fashion as they crumbled 10-1 to the Cleveland Indians as Michael Bourn hit a grand slam in the fifth inning.
The Detroit Tigers prevailed 6-2 against the Chicago White Sox on the back of home runs from Prince Fielder, Austin Jackson and Torii Hunter, while the New York Yankees succumbed 3-1 against the Texas Rangers, who had homers from AJ Pierzynski and David Murphy.
The faltering Boston Red Sox slumped 5-1 at Fenway Park against the Tampa Bay Rays, who are suddenly hot on their heels, half a game back in the race for AL East supremacy.
The Los Angeles Angels pipped the Minnesota Twins 1-0, Coco Crisp's two-run homer steered the Oakland Athletics towards a 4-3 victory against the Houston Astros, a pair of home runs from Eric Hosmer allowed the Kansas City Royals to sneak a 4-3 win over the Baltimore Orioles.