It was an all-round satisfactory outing for the Penguins as Evgeni Malkin scored on his return from injury, Chris Kunitz also netted and there was even a first ever assist for goaltender Tomas Vokoun.
The NHL record for consecutive wins is 17 - set by the Penguins in the 1992-93 season.
Andre Benoit, Guillaume Latendresse and Colin Greening scored for Ottawa Senators as they beat the New York Rangers 3-0 for their third straight win.
Ben Bishop notched his second career shutout with 24 saves.
Antii Niemi, meanwhile, claimed his second shutout in as many nights as the San Jose Sharks beat the Detroit Red Wings 2-0.
Joe Pavelski and Brent Burns got the goals for the Sharks.
Radim Vrbata had two goals and an assist as the Phoenix Coyotes romped to a 7-4 victory over the Nashville Predators.
Martin Hanzal, David Moss, Matthew Lombardi, Keith Yandle and Antoine Vermette also scored for the Coyotes, while Rostislav Klesla provided four assists.
Colin McDonald scored twice for the New York Islanders as they edged out the Philadelphia Flyers 4-3 via a shootout.
The Florida Panthers claimed a 5-4 shootout win over the Buffalo Sabres while the Edmonton Oilers beat the Columbus Blue Jackets 6-4.
The Vancouver Canucks were 4-1 winners over the Colorado Avalanche, the Los Angeles Kings beat the St Louis Blues 4-2 and the Toronto Maple Leafs saw off the Carolina Hurricanes 6-3.