The crushing defeat, Utah's worst at home in franchise history, ended a run of six straight wins at EnergySolutions Arena.
Marcus Morris scored 16 points for the Rockets off the bench, while Omer Asik pulled down 19 rebounds.
Danilo Gallinari poured in 27 points as the Denver Nuggets edged out the Indiana Pacers 102-101.
The Nuggets sealed the victory on an Andre Iguodala free throw with 0.4 seconds on the clock.
Paul George led the Pacers with 23 points and 10 rebounds.
There was also a tight finish in Washington where Isaiah Thomas sunk a floater with 1.9 seconds remaining to give the Sacramento Kings a 96-94 victory over the Washington Wizards.
Thomas had 22 points overall while Washington's Emeka Okafor led all scorers with 23 points and 15 rebounds.
Marc Gasol and Rudy Gay combined for 53 points as the Memphis Grizzlies overcame the Philadelphia 76ers 103-100.
Gasol had 27 points and Gay 26 for the Grizzlies, who were 17 points down at one stage, while Jerryd Bayless contributed 21.
Elsewhere, the Chicago Bulls beat the Charlotte Bobcats 93-85, the Golden State Warriors were 114-102 winners over the Toronto Raptors and the New Jersey Nets overcame the Orlando Magic 97-77.