Baltimore Ravens coach John will face younger brother and San Francisco 49ers boss Jim in New Orleans, the first time two brothers will stand on opposite sidelines as Super Bowl head coaches.
Both men are not keen on taking the spotlight away from their players though, and they are already questioning the merit of the game becoming the 'Harbaugh Bowl' in the world's media.
The questions will continue to rain in on the two siblings though, with the media sure to be keen to know exactly what the brothers will be saying to each other during Super Bowl week.
Ravens coach John Harbaugh insisted they both knew the significance of their achievements, but insisted there were no other great storylines in it.
"We aren't that interesting. There is nothing more to learn," John Harbaugh said. "It's just like any other family, really. I really hope the focus is not so much on that.
"We get it. It's really cool, and it's really exciting and all of that. It's pretty neat, but is it really going to be written about? It's not exactly like Churchill and Roosevelt!
"It's pretty cool but that's as far as it goes."
John says the two brothers have been too busy to talk about the Super Bowl as yet, but spoke of how competitive his younger brother is and how much his family were looking forward to the occasion.
"We haven't really talked yet, we've been so busy, but I've spoken to my mum and dad on the phone - that was a great conversation and I can't wait to see them down in New Orleans, it's going to be a great time.
"Everyone talks about how competitive he (Jim) is, he's an incredibly competitive person, he will fight you for anything, even a game of cards growing up, he will try anything to find a way to win no matter what.
"But it's really about the team. It's about the players. The more we focus on those guys, the better it is for everybody."
Jim Harbaugh, who called it a 'blessing and a curse' is also keener to focus on his 49ers players than on the two men who will be patrolling the sidelines come Super Bowl Sunday.
"The blessing because it's my brother's team and also personally I played for the Ravens," Jim Harbaugh said.
"The curse part would be that talk of two brothers playing in the Super Bowl and what that takes away from the players that are in the game."