Jamal Crawford scored 22 points with Blake Griffin adding 20 and 14 rebounds and Chris Paul scoring 16 for the Clippers, who improved to 6-2.
With Dwyane Wade limited by injury, LeBron James did his best to carry the Heat with 30 points, but the game got away from them late in the third, and early in the fourth the Clippers led 95-76.
The Memphis Grizzlies continued the best start to a season in franchise history as they rolled to a sixth straight win with a 107-97 victory over the Oklahoma City Thunder.
Rudy Gay led the charge with 28 points while Zach Randolph had collected 20 points and 11 rebounds before his evening was cut short by an ejection along with Oklahoma City's Kendrick Perkins.
Kevin Durant's season-high 34 points were in vain for the Thunder.
The Chicago Bulls needed overtime to see off the Phoenix Suns 112-106, but eventually did so behind 28 points and 14 rebounds from Carlos Boozer.
Luol Deng and Joakim Noah added 21 points apiece, Noah also collecting 12 rebounds.
James Harden continues to enjoy life in Houston as he registered at least 30 points for the third time in seven games, scoring exactly 30 in a 100-96 win over the New Orleans Hornets.
Omer Asik added 15 points and 12 rebounds.
The Boston Celtics hung on at the finish for a 98-93 win over the Utah Jazz, who missed a string of shots at the close.
Paul Pierce had 23 points for Boston with Jeff Green and Leandro Barbosa each adding 16.
Kemba Walker hit the game-winning shot with 0.7 seconds left as the Charlotte Bobcats beat the injury-ravaged Minnesota Timberwolves 89-87.
Walker finished with 22 points, none more important than those that came from a 19-foot jump-shot at the death.
The Detroit Pistons finally registered their first win of the season as they easily beat the Philadelphia 76ers 94-76 on the road.
Greg Monroe had 19 points and 18 rebounds in the win.
The Washington Wizards remain winless, however, as they went down 107-101 to the Dallas Mavericks in Texas.
Chris Kaman had 23 points and eight boards for the Mavs.
Brandon Jennings and Monta Ellis had 16 points each as the Milwaukee Bucks beat the Indiana Pacers 99-85.
Harrison Barnes had 19 points and 13 rebounds as the Golden State Warriors edged out the Atlanta Hawks 92-88.