Anfield legend Gerrard will miss the next three weeks with a hamstring injury and with Lucas Leiva also missing through a thigh strain, the Reds??? midfield is looking short of experience.
Henderson should partner Joe Allen in the centre of the pitch for Liverpool???s FA Cup fifth-round tie at Crystal Palace and the former Sunderland midfielder, who has been spoken about as a potential future captain, is relishing the prospect of the added responsibility.
“To lose Lucas first was a big blow because he has been outstanding for us since he came into the team as that defensive, holding midfielder,” said Henderson.
“Obviously Stevie (Gerrard) is a big loss, even though it is not as long (as Lucas), but there are some big games coming up that he might not be involved in.
“But it is another chance for people to come in and show what they are made of and slot straight into the team. Hopefully someone can do that.
“Maybe I need to take more responsibility with those two players gone.”
While Henderson???s most likely midfield partner is Joe Allen, Brendan Rodgers also has the option of moving Emre Can to that position from the back-three role in which he has so far excelled.
The German under-21 international was originally signed with the intention of playing in midfield for Liverpool but he has done well as a centre-back and Henderson feels it suits his skill set perfectly.
“Emre has been outstanding since he came into the team,” added Henderson.
“I really think that position has suited him at the right side of the three at centre-half.
“He has been outstanding there, especially defensively as a midfielder dropping back, and in driving with the ball he shows his strength and power going forward.”
Henderson has been a key player for Liverpool this season after a difficult initial period at the club and feels the fact he is being used as a central midfielder rather than in wide areas has helped that.
“Wherever I play I always try to improve, whether that is out wide or through the middle,” he added.
“I always give 100 per cent and I know each role I play really well so it doesn’t really matter what position I’m in.
“Of course being in the middle I am more comfortable and I am enjoying it there.”