The 40-year-old Argentine brings his glittering career to an end after 17 years as a professional.
Martinez was considered the best in the 160lbs division before persistent injuries – especially a knee problem – saw him lose to Miguel Cotto in June 2014.
It was his first defeat since losing to Paul Williams in December 2009, a run that began with ‘Marvellous’ becoming WBC and WBO champion after out-pointing Kelly Pavlik.
Martinez then avenged the loss to Williams with a stunning second-round knockout and went on to gain the WBC Diamond strap and make five defences, including a hat-trick of wins over British fighters.
He stopped Darren Barker in 11 rounds back October 2011, then Matthew Macklin retired after 11 rounds five months later, before he beat Martin Murray on points.
Martinez then took on Cotto and was put down three times in the first round, was then given a count in the ninth before it was ended in the 10th.
It left him with a professional record of 51-3-2-KO28 after he confirmed his retirement at the International Hall of Fame weekend, in Canastota, New York.