The 14th-seeded Australian saw off his Belgian opponent 6-1 6-3 at William HG FitzGerald Tennis Center to join Somdev Devvarman in the third round.
India's Devvarman was too strong for ninth-seeded Alexandr Dolgopolov, winning 6-3 7-6 (7/4).
In first round matches, there were wins for American trio Alex Kuznetsov, Jack Sock and Ryan Harrison.
Kuznetsov beat Russia's Alex Bogomolov Jr 3-6 6-4 6-3, Sock saw off Dutchman Igor Sijsling 6-4 6-2 and Harrison was too strong for former world number one Lleyton Hewitt, winning 6-3 7-5.
In the women's event, top-seeded wild card Angelique Kerber had few problems in knocking out qualifier Irina Falconi 6-2 6-3.
Britain's Heather Watson beat America's Alexandra Mueller 6-7 (5/7) 6-4 6-3 to set up a fourth round clash against fourth seed Alize Cornet, 6-1 6-3 conqueror of Yanina Wickmayer.
Elsewhere, fifth seed Sorana Cirstea advanced after Lesia Tsurenko retired while trailing 7-5, 1-1. There were also wins for Mona Barthel, Madison Keys, Monica Niculescu and Caroline Garcia.
Ekaterina Makarova defeated Eugenie Bouchard and Alison Riske saw off fellow American Vania King.
In later matches in the men's section, America's Sam Querrey came from a set down to defeat Uzbekistan's Denis Istomin 4-6 6-3 7-6.
Milos Raonic, Marinko Matosevic, Marcos Baghdatis, James Duckworth, Tim Smyczek and Dmitry Tursunov were all straight sets winners.