The third seed was beaten 6-4 6-1 in the second round in one hour and 47 minutes.
Number five seed Alexandra Cadantu progressed after she came from behind to beat wildcard Sabina Sharipova 1-6 6-3 6-3, while Croatian qualifier Donna Vekic booked her place in the third round with a 6-2 6-2 win over Spain's Lara Arruabarrena-Veci.
Poland's second seed Urszula Radwanska made light work of Vitalia Diatchenko with a 6-2 6-2 victory, while Kazakhstan's eighth seed Galina Voskoboeva beat Russia's Anna Chakvetadze 6-1 6-3.
Italy's Karin Knapp, who knocked out top seed Monica Niculescu on Tuesday, was defeated 6-2 6-2 by Eva Birnerova.
Other second-round winners on Wednesday were Alexandra Panova, who beat Misaki Doi 6-4 6-4, and Bojana Jovanovski, who overcame Eleni Daniilidou 6-3 6-7 (8/6) 6-3.