Garcia defeated former WBC champion Morales earlier this year and the Mexican veteran has activated a rematch clause.
The fight will headline the first night of boxing at the Barclays Center in Brooklyn, with Paulie Malignaggi set to defend his WBA welterweight title.
"I really wanted to put together a card that shows the diversity of Brooklyn, and to really showcase some of those fighters from and around the Brooklyn and greater New York area," said Golden Boy Promotions CEO Richard Schaefer.
"Erik feels that in his last fight, that when he came off of (gall bladder) surgery, that he wasn't at his best. He's convinced that he's going to beat Danny Garcia this time around, and you have the classic Puerto Rican-Mexican showdown."
Garcia followed up his points win over Morales by knocking Amir Khan out in the fourth round earlier this month.
The British fighter had hoped for a rematch with Garcia before the end of the year but that now appears to be out of the window.