Both athletes have achieved the mark once and Semenya needs to run inside a time of one minute 59.90 seconds in the women's 800 metres between now and the Games to qualify.
Pistorius, who competes on prosthetic legs, requires a time of 45.30secs or better in the 400m to become the first amputee athlete to run at the Olympics.
The 'Blade Runner' was relatively sluggish today [Friday], clocking 48.24secs to finish second behind Ranti Dekgate in his heat on day one of the South African Championships.
Running in lane eight, Pistorius struggled with a head wind in the home straight at the NMMU Stadium in Port Elizabeth and will hope to improve in the semis.
Semenya did not even have the chance to race as a raft of withdrawals meant her heat was cancelled and she automatically qualified for tomorrow's [Saturday] final.