Hartley still recalls the empty feeling of lifting the RBS 6 Nations title in the lobby of a Dublin hotel last year as he still nursed the bruises from a comprehensive defeat.
England had crossed the Irish Sea in pursuit of a Grand Slam but their own ambitions were ravaged by a ferocious Irish onslaught at the Aviva Stadium.
Twelve months on and England's new-look side have only a slim shot at the title but a home victory over Ireland - and a fourth win of the campaign - would represent a successful season.
England have beaten Ireland just once in their last eight championship meetings but Hartley insists Stuart Lancaster's men are ready to end that run.
"We've had a good tournament but if we don't finish off it will undo all the good work that we've done," Hartley said.
"People will soon forget about the brilliant result in Paris and the tricky wins in Scotland and Italy. They'll just think about the last time we played at Twickenham.
"We've learned that your last game is the one you're remembered by. I'd like to think we can go out with a bit of a bang this week.
"Ireland have got the better of us in recent years, winning seven out of eight championship games. We want to change that.
"Irish rugby is very strong at the moment. Ireland have got no fear. You can see that from their record at Twickenham. They'll come here, an experienced team, thinking they can win.
"We've had a big change up here with England. We're heading in the right direction. This could be the team to turn the tide."
England did return to Dublin in August to beat Ireland in a World Cup warm-up international but it was no consolation for the Six Nations humbling they received.
Ireland tore into England with a passion and a frenzy they had not produced all tournament to win 24-8 and deny Martin Johnson the rare achievement of winning a Grand Slam as a player and a coach.
Hartley vowed England had learned their lessons.
"Last year, we got caught like rabbits in the headlights. We weren't ready for them," Hartley said.
"This year we certainly won't get caught because we've talked about it this week, about the mindset going into this game.
"There is confidence in the group, confidence in the personnel involved. We want to play well so people remember this team for a good tournament."
England have won all three away fixtures in the same championship season for the first time and last weekend's triumph over France lifted Stuart Lancaster's men to fourth in the world.
Lancaster has succeeded in rebuilding the national team and restoring a sense of pride in English rugby following the debacle of the World Cup.
But Hartley wants to give the Twickenham crowd something to shout about.
England came so close in a thrilling game against Wales three weeks ago, only to be denied the chance of a last-gasp draw when David Strettle's 'try' was ruled out by the television match official.
"We've got this new group of players and we've gone and won three games away from home, which is fantastic," Hartley said.
"The atmosphere against Wales was the best I've experienced at Twickenham. Unfortunately we lost that game (against Wales).
"We want to turn that around this weekend and leave Twickenham with a good feeling. That's a massive motivation.
"The English rugby public has been brilliant. From the outset we've made it clear we want to change the perception of the team and I think we've done that.
"I'd like to think people are now right behind us.
"We want to play well, get Twickenham on its feet, get people right behind us so they remember this team for a good tournament."
England: B Foden (Northampton Saints); C Ashton (Northampton Saints), M Tuilagi (Leicester Tigers), B Barritt (Saracens), D Strettle (Saracens); O Farrell (Saracens), L Dickson (Northampton Saints); A Corbisiero (London Irish), D Hartley (Northampton Saints), D Cole (Leicester Tigers), M Botha (Saracens), G Parling (Leicester Tigers), T Croft (Leicester Tigers), C Robshaw (Harlequins, capt), B Morgan (Scarlets)
Replacements: L Mears (Bath Rugby), M Stevens (Saracens), T Palmer (Stade Francais), P Dowson (Northampton Saints), B Youngs (Leicester Tigers), C Hodgson (Saracens), M Brown (Harlequins)
Ireland: R Kearney (Leinster); T Bowe (Ospreys), K Earls (Munster), G D'Arcy (Leinster), A Trimble (Ulster); J Sexton (Leinster), E Reddan (Leinster); C Healy (Leinster), R Best (Ulster, capt), M Ross (Leinster), D O'Callaghan (Munster), D Ryan (Munster), S Ferris (Ulster), S O'Brien (Leinster), J Heaslip (Leinster)
Replacements: S Cronin (Leinster), T Court (Ulster), M McCarthy (Connacht), P O'Mahony (Munster), T O'Leary (Munster), R O'Gara (Munster), F McFadden (Leinster).