Five Jamaican athletes tested positive for banned substances this year, including the former 100m world record holder Asafa Powell.
The World Anti-Doping Agency (WADA) warned the Jamaican authorities they must address claims, made by a former senior official within the Jamaica Anti-Doping Commission, that drug-testing in the country is lax, or face expulsion from major competitions like the Olympics.
Jamaica Prime Minister Portia Simpson-Miller was so worried about the potential sanction that she wrote to WADA, promising that testing remained a priority.
Bolt has backed Simpson-Miller's intervention and the island's most famous sprinter now hopes the matter is closed.
"That will definitely help," the six-time Olympic champion said at a book signing session for his autobiography 'Faster than Lightning'.
"Anything that helps Jamaica to prove to the world that we are clean and that we are the best, I welcome fully.
"She says she is going to implement these things to make the sport better so it's a joy for me."
Expelling Jamaica from the Olympics would cause outrage on the Caribbean island, which has spawned some of the greatest athletes of all time.
It would also deny Bolt a shot at becoming the first sprinter to win three straight Olympic golds in the 100 metres.
"For me it would be really, really sad," the 27-year-old said.
"It would be really bad for the sport."
Bolt, who has always insisted he is clean, is reserving judgement on the athletes who have failed their tests until their cases are heard.
"Jamaicans are really pushing the limits and really run fast," he said.
"I think some of the times when there are drug problems a lot of people didn't do it on purpose but as an athlete you have to be aware and you have to take responsibility for these situations.
"There are a lot of cases going on now and we will see what comes out of them, we will see if it was done on purpose or not."