The bout will act as chief support to David Haye's heavyweight showdown with Tyson Fury.
Unbeaten Bury fighter Quigg claimed his 26th win and 19th inside the distance with a clinical third-round stoppage of William Prado in Bolton in June.
"It's a dream come true that my first world title fight will be in Manchester," said Quigg.
"It'll be a massive boost to have my fans there and, with Haye and Fury fighting too, it's a huge night to be involved in and a great stage to land a world title. I've worked so hard to get here and I'm going to grab this title with both hands."
Irish southpaw Andy Lee will also take on Italian Domenico Spada in an international middleweight contest on the undercard.
Lee, 29, who is ranked at number eight by the WBC, is a former world title challenger and has won two fights so far this year, outpointing Anthony Fitzgerald in February and then blowing away Darryl Cunningham in one round three months later.
Spada, 32, is ranked at three by the WBC, and has boxed for both the European and WBC interim middleweight titles.
Lee said: "This is a great next step for me in my career. Spada has been around the world scene for years now and has never before been stopped.
"He's a renowned tough guy with a solid chin and a great work ethic. Therefore, it is my aim to go out there, put on a show and become the first man to stop him."