The Yamaha rider saw his championship lead cut to 33 points last time out in Aragon and he remains vigilant of the threat posed by Repsol Honda duo Dani Pedrosa and Casey Stoner.
A demanding 'flyaway' triple-header starts at Motegi on Sunday - with the Malaysian and Australian Grands Prix also taking place in October - before the season concludes in Valencia on November 11.
The Mallorcan told motogp.com: "These three races are going to be really important for the championship and for the points, and our goal is to keep in the same line as the whole championship.
"We're always trying to fight for pole positions, and for podiums and victories.
"That is my goal, and if it is possible to win the races I am going to try, and if not then podiums will be okay in the last four races."
Lorenzo is refusing to use Stoner's return from a broken ankle as an excuse should he fail to win in Japan.
He added: "That is something that you cannot control.
"If Casey is fast enough he can win, and can take points off both Dani and me.
"One thing we can control is our performance and this is what we will try to control over these races.
"Normally here for Yamaha it is not so simple because we have some difficulties in acceleration, but we have good braking and corner entry, which are our strong points.
"Last year we made second place and finished not so far from Dani, and this year with the 1000cc we are a bit more competitive so we will try to be even closer."
Pedrosa has the chance to tie his own tally for the most number of podium finishes in a single year - one he set in 2004 with 13 rostrums.
But the 27-year-old knows he has to be at his very best to stake a title claim, saying: "It's important to have fun and enjoy it.
"We are doing good races and it's good also for the team because we have been doing progressively better during the championship.
"We are just trying to do the same, to keep focused and to ride well."
Meanwhile, a frustrated Stoner is keen to end his MotoGP career with some more wins following a frustrating lay-off that has scuppered his own title hopes.
The Australian earned seven podium finishes from the 11 races before his enforced six-week absence due to injuries suffered in a crash at Indianapolis in August.
He said: "Everyone has been asking me how the holiday at home was, but it's certainly been no holiday.
"You're lying up resting and you can't really do anything, even training was difficult so keeping ourselves fit for when we did return was tricky.
"Obviously it's really good to be back - it's not the way I wanted to finish my last season with the injury and having to sit out some races and not having a shot at the championship.
"It was definitely pretty disappointing for us to get the result that we did but we're here to do the best job we can from now until the end of the season.
"I feel good and fresh and we'll have to see how I get on with the bike tomorrow. Having this much time off it could be tricky for the first day."