And there, Yamaha Factory Racing's Jorge Lorenzo will be looking to extend his lead at the top of the championship standings.
This will be the 14th time the MotoGP field is set to race at the track, which is the shortest on the Grand Prix calendar. The circuit is known in particular for its infamous corner "The Corkscrew", which is a challenge for the riders and their machinery, as well as an absolute viewing pleasure for spectators.
Lorenzo, who recorded a dominant victory in Mugello last time out, building up a 19 point cushion in the championship, will be aiming to continue this good run of form, and once again get one over on his nearest rival Dani Pedrosa. Pedrosa, on board his Repsol Honda Team machine, has however found his form recently and seems to be gelling more with his bike, which will no doubt put him in strong contention to challenge for the win. His teammate Casey Stoner, who struggled with the set-up of his bike in Mugello and came eighth, will be hoping for a turnaround in fortunes at the track where he won last year in dominant fashion. After testing a new, more powerful engine last week, the Australian is hoping to utilise this during the forthcoming race to help his cause.
One person who does not look to have any troubles with his machine is Monster Yamaha Tech 3's Andrea Dovizioso, after recording his third consecutive podium in a row at his home track. The Italian will be looking to continue in this vein and mix it up once more with the factory bikes up front. Teammate Cal Crutchlow will aim to bring his practice form into a race, as the Brit has recently struggled to achieve the results he has been hoping for. He stated after the Mugello test that he has been working on his early race-pace with a full tank, and hopes to get a better start at the Laguna track, to aid him mount a serious podium challenge.
Another team looking to make big strides in the US is the Ducati Team, which will be using a new engine to try and combat the bike's handling issues. Both Valentino Rossi and Nicky Hayden have won at the track, and will be hoping that the new improvements will let them mount at least a podium challenge, which they were close to last time out in Mugello. LCR Honda MotoGP's Stefan Bradl arrives fresh off his best ever MotoGP finish in fourth, yet will be contesting the Californian circuit for the first time. The rookie, who has already scored more points this year than any German GP rider in a single season, has however done a private test on the track with a road bike to familiarise himself with it.
San Carlo Honda Gresini's Álvaro Bautista will aim to put his Mugello weekend behind him as he looks to re-find some of the form he had shown earlier in the season, and not crash out of the race as he did last year. Yamaha's Ben Spies, whose season has been plagued with bad luck, will no doubt see this as a springboard for his championship campaign. He came fourth at the track last year, and will once again look to soak up the home support for a good result.
Unfortunately, Pramac Racing Team rider Héctor Barberá will miss out on this first American round, due to his recent training incident where he fractured the left fibula and tibia. Barberá underwent successful surgery at the Instituto Universitario USP Dexeus last Sunday and the unlucky Spaniard has began the rehabilitation and should be able to run a race in 4 or 6 weeks.
He will be replaced by Spanish rider Toni Elías, who already rode for the Pramac Racing Team in 2008, achieving two amazing podiums in Brno and in Misano. The 29-year-old rider made his international racing debut in the 125cc World Championship in 2000, finishing 3rd in 2001 and taking his first win in the Dutch TT at the prestigious Assen circuit. In the following years, Elías was able to clinch to the inaugural Moto2 World Championship at the Malaysian Grand Prix with three rounds to spare. This year, Toni was riding with the Aspar Racing Team aboard on Suter machine in Moto2 class but both sides have announced that they were parting ways. Therefore Elías, until few days ago, was a rider without a bike to run with. Now he has the opportunity to show his potential at the spectacular Laguna Seca.
Cardion AB Racing's Karel Abraham is expected to race once again, after a four-race absence due to his hand injuries.
The CRT field will relish the opportunity to race at the short Laguna Seca circuit, as it should close the gap somewhat to their factory counterparts. Randy de Puniet and Aleix Espargaró on their Power Electronics Aspar ART machines will undoubtedly remain towards the top of the CRT pile, and will as usual face a stiff challenge from Speed Master's Mattia Pasini and San Carlo Honda Gresini's Michele Pirro.
NGM Mobile Forward Racing's Colin Edwards will line up with his Suter-BMW machine despite testing an FTR-Honda and BQR-FTR bike in Mugello, and will hope to put in a good showing in front of his home fans. Also racing alongside him will be Came IodaRacing Project's Danilo Petrucci, Paul Bird Motorsport's James Ellison and Avintia Blusens' Yonny Hernandez and Iván Silva. US-based bike racing team Attack Performance Racing will be entering as a wildcard with rider Steve Rapp on board an in-house built, Kawasaki powered machine.