Pedrosa finished eighth in Italy in a race that marked his return from a broken collarbone suffered at Le Mans in May, which forced him to sit out three rounds and wrecked his title aspirations in the process.
The Repsol Honda rider was victorious at the German Grand Prix 12 months ago, and believes returning to a happy hunting ground can only help his cause as he bids to return to full fitness.
"The last race in Mugello was good because after a long time without racing, I saw that I haven't lost the ability to go fast," said Pedrosa, who has struggled with a string of injuries in recent years.
"I have to regain fitness and this week I have worked hard.
"I've always had very good races at Sachsenring and it's good to get to a track where you know you can do well.
"Contrary to Mugello, Germany is all almost left hand corners and this must help me.
"Last year, we had a great race there and hopefully we can do a good job again during practice, hope nothing goes wrong and come out with a good chance for the race."
Yamaha's Jorge Lorenzo closed the gap to championship leader Casey Stoner (Repsol Honda) with a fantastic win Mugello, although he has never triumphed at the Sachsenring.
The reigning world champion has finished second in consecutive races in Germany, but it remains one of two circuits he has never won at during his impressive premier-class career.
But the Spaniard's victory in Italy, when he pulled great moves on the Hondas of Andrea Dovizioso and Stoner to hit the front, will give him belief that he can catch the Australian, who sits 19 points clear in the standings.
Stoner has been in fine form this season, claiming four race wins and three other podium finishes in the opening eight rounds.
Ducati's Valentino Rossi, meanwhile, cannot be discounted at a circuit where he has thrived down the years.
He has won four grands prix at the Sachsenring, and will celebrate his 250th grand prix on Sunday.