Last season's race had to be cancelled following political unrest which resulted in the deaths of a number of protesters.
That has led to Nabeel Rajab, vice-president for the Bahrain Centre for Human Rights, claiming a campaign will be launched urging teams and drivers to stay away from the event that is planned for April 20-22.
They are supported by Human Rights Watch who insist F1's world governing body the FIA "should consider the serious abuse of human rights in Bahrain and the fact to this day authorities continue to suppress pro-democracy protests".
Speaking to Arabian Business, HRW spokesperson Mariwan Hama-Saeed added: "I doubt Formula One can be a success in a country where serious human rights abuses have been committed.
"The political situation is unstable and polarised in Bahrain. We are very concerned about the government's commitment to implement meaningful reform."
However, following the release of an independent report in November that was commissioned by the king of Bahrain to look into the events that occurred last year, the authorities insist they are acting.
A spokesman for the Bahrain International Circuit said: "The report found evidence of human rights violations and made certain general and specific recommendations.
"The government has fully acknowledged the findings of the report and is acting swiftly and convincingly on the recommendations.
"The Bahrain Grand Prix forms a fundamental part of the local economy.
"It is supported by an overwhelming majority of people from all sections of society in Bahrain and represents a symbol of national unity.
"The independent report was a milestone for Bahrain and we will now work tirelessly to ensure the race is a great success."