Vettel produced another stunning drive to claim his ninth win this year, 19th of his career, and 15th from pole - the latter statistic drawing him level alongside the legendary Jim Clark.
The 24-year-old led every single lap of the race to leave him one point shy of becoming the youngest back-to-back and double world champion in Formula One history.
Vettel is now 124 points clear of McLaren's Jenson Button, who was a commendable second with the Briton on the podium for the fourth race in succession.
But with just 125 points available, Red Bull can plan for a party in Suzuka in a fortnight, in particular as Vettel has won the last two Japanese Grands Prix.
Asked if this season was a magical one, Vettel said: "Magic? I don't know, maybe for some people.
"It has been an incredible year for us, an incredible record for both of us (team-mate Mark Webber) in terms of reliability.
"We have had no problems with the car, the engine has been perfect from start to finish, so touch wood, nothing has gone wrong so far this year.
"It does need a lot of small things to come together to make sure you have an incredible season like we have had so far.
"It's been very enjoyable. Everyone has been extremely disciplined in a way, target-orientated and we've all enjoyed it.
"Those things sum it up pretty well, but of course we hope to carry on like that, carry the momentum into the next races, and into next season as well."
Not even a safety car for a crash involving seven-times champion Michael Schumacher in his Mercedes, at a time when Vettel held a 19-second cushion over Button on lap 30, halted his charge.
Come the end, Button finished just 1.7secs adrift, although Vettel insisted he was "in control" of the situation.
Behind the leading duo Red Bull's Mark Webber was third, Fernando Alonso fourth, whilst Lewis Hamilton was fifth after yet another incident, and again involving Felipe Massa.
The Brazilian ended up with a puncture after being caught by the front wing of Hamilton's McLaren, sparking a showdown in the pen where the drivers conduct post-race tv and radio interviews.
Vettel, instead, served as a shining example to both men of how to conduct oneself, both on and off the track.
The German, who has previously buried his head in the sand when it has come to the title scenario, now knows exactly what is required.
"I wasn't thinking about the title in the race," said Vettel.
"I had made it quite clear beforehand that it wasn't important to know where other people were.
"Obviously I was given the gaps to Jenson, and then the race order at the end, so crossing the line I didn't know whether I had done enough or not.
"It was a little similar to what happened in Abu Dhabi last year (when he won the title). I didn't know in which position people had to finish.
"For Japan, I'm obviously smart enough to work it out myself now!"