At present, a 22-race schedule is on the cards, although three in New Jersey, Korea and Mexico are currently provisional, with ratification not due until early December.
Should the exhaustive campaign be given the green light, Brawn knows he will face no choice but to take on fresh faces to cope with the workload.
"Twenty-two will definitely reach the point where we start to rotate people because it's not just 22 races, there are four tests as well," said Brawn.
"The pre-season also starts a couple of weeks earlier than usual, so with testing from the end of January and then going racing through to the end of November, it is pretty heavy.
"It means we are looking at strengthening the team so we can start some rotation.
"There are other motorsports that do, for instance I think NASCAR has several teams, so it's feasible. You just need to organise yourself."
Asked as to the required numbers to strengthen, Brawn added: "It would be mainly mechanics and garage technicians and so on, so you are talking about half a dozen to eight people.
"The challenge is to always make sure the performance doesn't alter, particularly with pit stops.
"The rotation at pit stops is something we've focused on this year, so if somebody is ill or can't make a race for some reason, then we don't get an immediate drop in the performance of the crew.
"So Ron (Meadows, team manager), who has been looking after all of that, makes sure he's always got some people he can substitute, off the bench so to speak, ready to come on.
"It's not huge numbers, but enough to give us some scope."
The key question is whether Brawn will be around next season to oversee such changes.
There have been rumours since the start of this campaign Brawn might step aside, particularly with the arrival of Paddy Lowe from McLaren as executive director (technical).
If Brawn remains in charge, skipping a race or two would give Lowe, or whoever else might be in the frame, the platform to eventually step up.
Asked as to his plans for 2014, and if he would give himself a break, Brawn added: "Well, that would be a good idea.
"With the number of people we've got, I'm sure we could do that.
"Although at engineering level it's a little more difficult to have rotation.
"Of course, if we have a problem then we would find someone to come in, but in engineering it's quite diffiult.
"I think where we intend to focus there is to give the guys more support at the factory so they can have time off when they get back.
"So they'll still do the events, but perhaps not spend so much time at the factory so they can recover.
"For some guys, it's rather like the drivers, you can't substitute certain members of the team.
"As for me, hopefully I won't be able to be substituted."