Throughout a 12-and-a-half-year career in Formula One in which he has competed in 218 grands prix, Button has won the world title, 13 races and stepped on to the podium 45 times overall.
Yet remarkably, in 12 previous attempts, a top-three finish in the British Grand Prix still eludes him, never mind victory.
Understandably, it is something that has played on Button's mind over the years, and as we fast approach this weekend's event at what is expected to be a wet Silverstone, it does so again.
"I've always thought about what it would be like to win the British Grand Prix. I've imagined it, of course," said the 32-year-old McLaren driver.
"You never know what it will be like until it happens. When I was a kid I thought about racing at Monaco and winning that race.
"And I did it in style by parking in the wrong place and running to the start-finish line. I didn't know I was going to do that.
"Of course, I haven't even been on the podium yet, but winning it would be very special for me.
"(Team-mate) Lewis (Hamilton) won it in '08. That was the last time a British driver did so.
"Now I want to win it. That has to be my aim for this weekend, and it would be something to give to the fans.
"Winning when you have a lot of supporters there, people who have been supporting you for so many years and have really lifted you in difficult times, would mean so much."
Button has already admitted he will shed a tear this weekend if he does break his podium jinx, but knows he cannot afford to let such a hoodoo get to him.
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"It is surprising I've not been on the podium. I've had two fourths, and in my first British Grand Prix I was fifth," said Button.
"Last year we had a really good chance of getting on the podium, but then we had the issue (with a front tyre at a pit stop).
"But I wouldn't say it's something I'm worried about, that it upsets me too much, that I'm feeling negative about never having won it.
"I go into the British Grand Prix excited about the race, excited about fighting in it again in a few days' time."
The ideal scenario on Sunday for the majority of a 125,500 sell-out crowd would be to have Button and Hamilton on the podium, maybe even Force India's Paul di Resta if the Scot can blaze his own trail.
It has been 13 years since two Britons finished in the top three at Silverstone, with Hamilton admitting: "It would definitely be very historic to have us both up there."
Winner of the British GP in 2008 en route to his world title that year, Hamilton has no doubts Button will end his home hoodoo.
Hamilton said: "Let's not forget Jenson has been around for a long, long time.
"He has represented the country for a long time, a lot longer than I have in F1, so he's done a lot of for the country.
"Although he's not been on the podium, it's not been for a lack of ability, it's been for a lack of opportunity, the lack of a car, reliability and stuff.
"But his day will come, and when it does, I hope I'm there as well."
Hamilton has his own demons to conquer after his latest incident with Williams' Pastor Maldonado in Valencia 10 days ago.
The 27-year-old was shunted into a wall by the Venezuelan just a lap and a half from the finish as they battled over third place, leaving him 23 points behind championship leader Fernando Alonso.
Hamilton maintains there is no hangover, adding: "There is just sheer excitement to get back on it, to get back to where I was because my consistency up until then had been great.
"To have eight grands prix and only one DNF, and it wasn't because I drove into a wall, is quite comforting."