Imada, who lost to Zach Johnson in a play-off last year after hooking his second shot into the water, fired a five-under-par 67 - which included six birdies and just one bogey - to finish at 15 under par overall.
Perry, who carded a final-round 69, found water with his second shot at the first play-off hole and Imada held his nerve to claim the title.
"It's definitely an unbelievable feeling," said Imada. "I had one thing on my mind coming into this week - to get a win - and to actually do it is just an unbelievable feeling.
"I never really believed in destiny, but I'm starting to believe it now."
Colombian Camilo Villegas carded a 66 to finish third at 14 under, with Jonathan Byrd (70) one stroke further back.