The Valencian extended his overnight lead by three shots over nearest challenger Fabrizio Zanotti with a seven-under-par round that contained eight birdies and his first bogey in 35 holes at the 16th.
An opening par was followed by three straight birdies at the Stadium Course before Del Moral, looking to qualify for the fourth time in six years, picked up shots at the seventh, 11 and 12th holes.
His solitary blemish on Thursday was preceded and followed by birdies as he moved onto a 21-under-par overall total, four shots clear of Zanotti, who carded 68.
"I'm not stressed at all on that course," Del Moral said on the European Tour website. "I'm playing every shot really calm and positive and I'm not making many mistakes out there.
"I feel like if I have any putts between five and 10 metres I have a chance so I don't need to go for pins and when you don't have to go for pins it's a lot easier.
"I have got a lot of trust in my putter and hopefully it will be the same (on Friday)."
An eagle at the par five 15th was the highlight of the day for Zanotti, while he also collected three birdies and a bogey.
The Paraguayan is himself four shots clear of England's James Morrison and Italy's Marco Crespi, who are in a tie for third on 13 under par overall.
Currently there are 32 players, including 11 rookies, in contention to earn a 2014 European Tour card, with the top 25 and ties qualifying.
Stuart Manley, on 12 under par, and fellow Britons Alastair Forsyth and and Adam Gee, one shot further back, appear well poised to qualify.
Daniel Brooks, Simon Wakefield, Jack Doherty, James Heath and Chris Paisley are the other British players currently in the top 25.