The Portuguese will be expected to deal comfortably with their opponents in Braga, but they go into the contest having suffered an early shock last week in Luxembourg, falling a goal behind to the unfancied hosts in the 13th minute before bouncing back to win 2-1.
Azerbaijan, meanwhile, secured a 1-1 draw with Israel in Baku and Custodio has stressed Portugal are not about to take the so-called minnows lightly on Tuesday evening.
"Azerbaijan are a good team who drew with Israel," said Custodio on www.fpf.pt.
"We have to be very mindful of this team."
The 29-year-old Braga player admits things did not go entirely as planned for Portugal in Luxembourg but has emphasised that the team's job was ultimately done in terms of sealing a victory, and is confident they will receive the full backing of the crowd at his home ground on Tuesday.
"The main objective (against Luxembourg) was accomplished," Custodio said.
"We claimed the three points and that was the most important thing.
"The Braga public will appear en masse and support us, not only in good times but also in bad."
Israel's match on Tuesday is at home against Russia, who defeated Northern Ireland 2-0 in Moscow in their opening qualifier last Friday.
It is a tough-looking assignment for the Israelis, but midfielder Hen Ezra believes the team have it in them to bounce back from the disappointment of the Azerbaijan result and beat the Russians.
"There is not much to talk about (regarding the Azerbaijan game), everyone knows we're disappointed," said Ezra, quoted on football.org.il.
"Against Russia we hope the fans will come and help us and they should be optimistic - we really think we can do it and win.
"Russia are a strong team, though. Everyone knows they are strong, and we will have to prepare as well as possible."
The other game in Group F on Tuesday sees Northern Ireland take on Luxembourg in Belfast.